Buprenorfina: Una terapia alternativa en la abstinencia por drogas
DOI:
https://doi.org/10.23857/dc.v7i5.2232Palabras clave:
Buprenorfina, abstinencia de drogas, terapia alternativa, adicción, opioides.Resumen
La buprenorfina es un fórmaco del conjunto de los opioides, eficaz para el procedimiento de la adicción a otros opioides como la morfina y la heroína de igual manera al procedimiento con metadona. En los íºltimos años se aprobó el uso de buprenorfina como parte de una terapia alternativa de la abstinencia de drogas, pues te ayuda a aliviar el dolor y controlar la adicción de los pacientes, al igual que lo hacía la metadona, por lo que buprenorfina se ha vuelto un medio de tratamiento. La investigación realizada utilizó un enfoque analítico, ya que evaluó las variables de la investigación como lo son la buprenorfina, aspectos positivos y negativos de la misma, ademós de los previos estudios para posibles métodos del tratamiento de abstinencia por drogas con otras sustancias farmacológicas, en paralelo de un conjunto de antecedentes experimentales, documentales y doctrinarios del órea médica en esta temótica. Se infiere a partir de esta investigación, que la buprenorfina como medio de tratamiento para la adicción de otros opioides es fundamental, pero debe ser bajo los parómetros que necesite el paciente, pues, aunque la buprenorfina ayude a tratar otras adicciones de la misma naturaleza, el mal uso de la misma podría eclipsar a la primera adicción y volverla mós grave, no obstante, su uso es recomendable bajo condiciones médicas pertinentes y diligentes.Citas
Tellioglu, T. (2021). Buprenorphine. Samhsa.gov. https://www.samhsa.gov/medication-assisted-treatment/medications-counseling-related-conditions/buprenorphine
Ling, W. (2012). Buprenorphine implant for opioid addiction. Pain Management, 2(4), 345–350. https://doi.org/10.2217/pmt.12.26
Souza, Mario, M., Barriga, D., Lino, S., Cruz, G., Manuel, V., & Souza, M. (2007). Terapí©utica sustitutiva con buprenorfina para abusadores / adictos a opiáceos. Rev Mex Neuroci, 8(4). https://www.medigraphic.com/pdfs/revmexneu/rmn-2007/rmn074j.pdf
Gowing, L., Ali, R., White, J. M., & Mbewe, D. (2017). Buprenorphine for managing opioid withdrawal. Cochrane Database of Systematic Reviews, 1(1). https://doi.org/10.1002/14651858.cd002025.pub5
Kleber, H. (2007). Pharmacologic treatments for opioid dependence: detoxification and maintenance options. Neuropsychiatric Manifestations of Neurodegenerative Disease, 9(2), 455–470. https://doi.org/10.31887/dcns.2007.9.2/hkleber
Alcohol and Drug Fundation. (2020). Buprenorphine - Alcohol and Drug Foundation. Adf.org.au. https://adf.org.au/drug-facts/buprenorphine/
ALBERT EINSTEIN COLLEGE OF MEDICINE. (2017). Integrating Buprenorphine Treatment for Opioid Use Disorder in Primary Care. https://ciswh.org/wp-content/uploads/2017/06/Buprenorphine-Implementation-Manual-for-Primary-Care-Settings-.pdf
Agapoff, J. (2019). Outpatient buprenorphine induction and maintenance treatment for kratom dependence: A case study. Journal of Substance Use. https://www.tandfonline.com/doi/abs/10.1080/14659891.2019.1638459
Brennan, T. (2019, October 7). Transitioning from Methadone to Buprenorphine - PCSS. Providers Clinical Support System. https://pcssnow.org/education-training/training-courses/transitioning-from-methadone-to-buprenorphine/
Cisewski, D. H., Santos, C., Koyfman, A., & Long, B. (2019). Approach to buprenorphine use for opioid withdrawal treatment in the emergency setting. The American Journal of Emergency Medicine, 37(1), 143–150. https://doi.org/10.1016/j.ajem.2018.10.013
Hassan, R., Pike See, C., Sreenivasan, S., Mansor, S. M., Mí¼ller, C. P., & Hassan, Z. (2020). Mitragynine Attenuates Morphine Withdrawal Effects in Rats—A Comparison With Methadone and Buprenorphine. Frontiers in Psychiatry, 11. https://doi.org/10.3389/fpsyt.2020.00411
Klaire, S., Zivanovic, R., Barbic, S. P., Sandhu, R., Mathew, N., & Azar, P. (2019). Rapid Microâ€Induction of Buprenorphine/Naloxone for Opioid Use Disorder in an Inpatient Setting: A Case Series. The American Journal on Addictions, 28(4), 262–265. https://doi.org/10.1111/ajad.1286
Levin, F. (2019, October 8). Myths and Misconceptions of Medication-Assisted Treatment - PCSS. Providers Clinical Support System. https://pcssnow.org/education-training/training-courses/myths-misconceptions-medication-assisted-treatment/
Mizuno, T., McPhail, B. T., Kamatkar, S., Wexelblatt, S., Ward, L., Christians, U., Akinbi, H. T., & Vinks, A. A. (2020). Physiologic Indirect Response Modeling to Describe Buprenorphine Pharmacodynamics in Newborns Treated for Neonatal Opioid Withdrawal
Syndrome. Clinical Pharmacokinetics, 60(2), 249–259. https://doi.org/10.1007/s40262-020-00939-2
Randhawa, P. A., Brar, R., & Nolan, S. (2020). Buprenorphine–naloxone microdosingâ€: an alternative induction approach for the treatment of opioid use disorder in the wake of North America’s increasingly potent illicit drug market. Canadian Medical Association Journal, 192(3), E73–E73. https://doi.org/10.1503/cmaj.74018
Salsitz, E. (2020, November 13). Patient Wants To Stop Taking Buprenorphine - PCSS. Providers Clinical Support System. https://pcssnow.org/education-training/training-courses/patient-wants-to-stop-taking-buprenorphine/
SAMHSA. (2021). Buprenorphine. Samhsa.gov. https://www.samhsa.gov/medication-assisted-treatment/medications-counseling-related-conditions/buprenorphine
Saxon, A. (2019). PCSS Learning: Methadone and Buprenorphine-Associated Drug-Drug Interactions. Pcssnow.org. https://learning.pcssnow.org/p/MethBupDrugDrugInteractions
Tierney, M. (2019, October 9). Integrating Agonist Treatment in Primary Care and Mental Health Settings: A Clinical Model - PCSS. Providers Clinical Support System. https://pcssnow.org/event/integrating-agonist-treatment-in-primary-care-and-mental-health-settings-a-clinical-model/
Wolfrum, L. A., Nordmeyer, A. S., Racine, C. W., & Nichols, S. D. (2019). Loperamide-Associated Opioid Use Disorder and Proposal of an Alternative Treatment with Buprenorphine. Journal of Addiction Medicine, 13(3), 245–247. https://doi.org/10.1097/adm.0000000000000472
Hassan, R., Pike See, C., Sreenivasan, S., Mansor, S. M., Mí¼ller, C. P., & Hassan, Z. (2020b). Mitragynine Attenuates Morphine Withdrawal Effects in Rats—A Comparison With Methadone and Buprenorphine. Frontiers in Psychiatry, 11. https://doi.org/10.3389/fpsyt.2020.00411
Herring, A. A., Perrone, J., & Nelson, L. S. (2019). Managing Opioid Withdrawal in the Emergency Department With Buprenorphine. Annals of Emergency Medicine, 73(5), 481–487. https://doi.org/10.1016/j.annemergmed.2018.11.032
Ahmed, S., Bhivandkar, S., Lonergan, B. B., & Suzuki, J. (2020). Microinduction of Buprenorphine/Naloxone: A Review of the Literature. The American Journal on Addictions, 30(4), 305–315. https://doi.org/10.1111/ajad.13135
Fishman, M. A., & Kim, P. S. (2018). Buprenorphine for Chronic Pain: a Systemic Review. Current Pain and Headache Reports, 22(12). https://doi.org/10.1007/s11916-018-0732-2
Dunkley, C. A., Carpenter, J. E., Murray, B. P., Sizemore, E., Wheatley, M., Morgan, B. W., Moran, T. P., & Steck, A. (2019). Retrospective Review of a Novel Approach to Buprenorphine Induction in the Emergency Department. The Journal of Emergency Medicine, 57(2), 181–186. https://doi.org/10.1016/j.jemermed.2019.03.029
Ritvo, A. D., Calcaterra, S. L., & Ritvo, J. I. (2020). Using Extended-Release Buprenorphine Injection to Discontinue Sublingual Buprenorphine: A Case Series. Journal of Addiction Medicine, 15(3), 252–254. https://doi.org/10.1097/adm.0000000000000738
Coe, M. A., Lofwall, M. R., & Walsh, S. L. (2019). Buprenorphine Pharmacology Review: Update on Transmucosal and Long-acting Formulations. Journal of Addiction Medicine, 13(2), 93–103. https://doi.org/10.1097/adm.0000000000000457
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